phosphorylated mtor Search Results


phosphorylated mtor sc-293133 antibody  (Cosmo Bio USA)
90
Cosmo Bio USA phosphorylated mtor sc-293133 antibody
Phosphorylated Mtor Sc 293133 Antibody, supplied by Cosmo Bio USA, used in various techniques. Bioz Stars score: 90/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
https://www.bioz.com/product/phosphorylated+mtor/pm32916531-51-27-30?v=Cosmo+Bio+USA
Average 90 stars, based on 1 article reviews
phosphorylated mtor sc-293133 antibody - by Bioz Stars, 2026-08
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phosphorylation of two major downstream targets of mtor, p70s6 kinase (p70s6k) and eif4e-binding protein (4ebp2)  (Garelick Farms)
90
Garelick Farms phosphorylation of two major downstream targets of mtor, p70s6 kinase (p70s6k) and eif4e-binding protein (4ebp2)
Trimethylamine‐ N ‐oxide ( TMAO ) reduced the expression of synaptic plasticity‐related proteins by down‐regulating the activity of the <t>mTOR</t> signalling pathway. (a) Synaptophysin ( SYN ), postsynaptic density 95 ( PSD ‐95) and N ‐methyl‐ d ‐aspartate 1 ( NMDAR 1) were shown by immunohistochemical staining in the hippocampus. The expression levels of SYN , NMDAR 1 and PSD ‐95 were significantly decreased in the P8‐C group compared with the R1‐C group. There was a significant decrease in the expression of these synaptic‐associated proteins in the TMAO groups compared with their control groups (scale bar = 50 μm). (b) The expression levels of SYN , NMDAR 1 and PSD ‐95 were assayed by Western blotting. To examine the possible mechanism involved in the decline of synaptic‐associated proteins, three proteins ( mTOR <t>,</t> <t>p70s6k</t> and 4 EBP 2) of the mTOR signalling pathway were assessed by RT – PCR and Western blotting. (Figure A) The mRNA levels of mTOR , p70s6k and 4 EBP 2 were not significantly different in the groups assessed by RT – PCR . (c) Phosphor‐ mTOR / mTOR , phosphor‐p70s6k/p70s6k and phosphor‐4 EBP 1/4 EBP 2 were monitored by Western blotting. β‐Actin was used as a loading control. The bands in the Western blotting were scanned, and the ratios of optical density of specific bands and β‐actin are illustrated. TMAO inhibited the active form of mTOR , p70s6k and 4 EBP 2 (phosphorylated). Data are shown as the mean ± SEM ( n = 6 each group, two‐way ANOVA , comparisons between two groups were made using Tukey's multiple comparison test. ** p < .01). The samples derived from the same experiment and the blots were processed in parallel
Phosphorylation Of Two Major Downstream Targets Of Mtor, P70s6 Kinase (P70s6k) And Eif4e Binding Protein (4ebp2), supplied by Garelick Farms, used in various techniques. Bioz Stars score: 90/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
https://www.bioz.com/product/phosphorylated+mtor/pmc06052480-19-12-20?v=Garelick+Farms
Average 90 stars, based on 1 article reviews
phosphorylation of two major downstream targets of mtor, p70s6 kinase (p70s6k) and eif4e-binding protein (4ebp2) - by Bioz Stars, 2026-08
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phosphorylation of mtor  (Merck KGaA)
90
Merck KGaA phosphorylation of mtor
Trimethylamine‐ N ‐oxide ( TMAO ) reduced the expression of synaptic plasticity‐related proteins by down‐regulating the activity of the <t>mTOR</t> signalling pathway. (a) Synaptophysin ( SYN ), postsynaptic density 95 ( PSD ‐95) and N ‐methyl‐ d ‐aspartate 1 ( NMDAR 1) were shown by immunohistochemical staining in the hippocampus. The expression levels of SYN , NMDAR 1 and PSD ‐95 were significantly decreased in the P8‐C group compared with the R1‐C group. There was a significant decrease in the expression of these synaptic‐associated proteins in the TMAO groups compared with their control groups (scale bar = 50 μm). (b) The expression levels of SYN , NMDAR 1 and PSD ‐95 were assayed by Western blotting. To examine the possible mechanism involved in the decline of synaptic‐associated proteins, three proteins ( mTOR <t>,</t> <t>p70s6k</t> and 4 EBP 2) of the mTOR signalling pathway were assessed by RT – PCR and Western blotting. (Figure A) The mRNA levels of mTOR , p70s6k and 4 EBP 2 were not significantly different in the groups assessed by RT – PCR . (c) Phosphor‐ mTOR / mTOR , phosphor‐p70s6k/p70s6k and phosphor‐4 EBP 1/4 EBP 2 were monitored by Western blotting. β‐Actin was used as a loading control. The bands in the Western blotting were scanned, and the ratios of optical density of specific bands and β‐actin are illustrated. TMAO inhibited the active form of mTOR , p70s6k and 4 EBP 2 (phosphorylated). Data are shown as the mean ± SEM ( n = 6 each group, two‐way ANOVA , comparisons between two groups were made using Tukey's multiple comparison test. ** p < .01). The samples derived from the same experiment and the blots were processed in parallel
Phosphorylation Of Mtor, supplied by Merck KGaA, used in various techniques. Bioz Stars score: 90/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
https://www.bioz.com/product/phosphorylated+mtor/pm37597422-121-2-12?v=Merck+KGaA
Average 90 stars, based on 1 article reviews
phosphorylation of mtor - by Bioz Stars, 2026-08
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phosphorylated mtor (#ab11221) antibody  (AbSci LLC)
90
AbSci LLC phosphorylated mtor (#ab11221) antibody
Trimethylamine‐ N ‐oxide ( TMAO ) reduced the expression of synaptic plasticity‐related proteins by down‐regulating the activity of the <t>mTOR</t> signalling pathway. (a) Synaptophysin ( SYN ), postsynaptic density 95 ( PSD ‐95) and N ‐methyl‐ d ‐aspartate 1 ( NMDAR 1) were shown by immunohistochemical staining in the hippocampus. The expression levels of SYN , NMDAR 1 and PSD ‐95 were significantly decreased in the P8‐C group compared with the R1‐C group. There was a significant decrease in the expression of these synaptic‐associated proteins in the TMAO groups compared with their control groups (scale bar = 50 μm). (b) The expression levels of SYN , NMDAR 1 and PSD ‐95 were assayed by Western blotting. To examine the possible mechanism involved in the decline of synaptic‐associated proteins, three proteins ( mTOR <t>,</t> <t>p70s6k</t> and 4 EBP 2) of the mTOR signalling pathway were assessed by RT – PCR and Western blotting. (Figure A) The mRNA levels of mTOR , p70s6k and 4 EBP 2 were not significantly different in the groups assessed by RT – PCR . (c) Phosphor‐ mTOR / mTOR , phosphor‐p70s6k/p70s6k and phosphor‐4 EBP 1/4 EBP 2 were monitored by Western blotting. β‐Actin was used as a loading control. The bands in the Western blotting were scanned, and the ratios of optical density of specific bands and β‐actin are illustrated. TMAO inhibited the active form of mTOR , p70s6k and 4 EBP 2 (phosphorylated). Data are shown as the mean ± SEM ( n = 6 each group, two‐way ANOVA , comparisons between two groups were made using Tukey's multiple comparison test. ** p < .01). The samples derived from the same experiment and the blots were processed in parallel
Phosphorylated Mtor (#Ab11221) Antibody, supplied by AbSci LLC, used in various techniques. Bioz Stars score: 90/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
https://www.bioz.com/product/phosphorylated+mtor/10__1096_slash_fj__202001992r-69-9-20?v=AbSci+LLC
Average 90 stars, based on 1 article reviews
phosphorylated mtor (#ab11221) antibody - by Bioz Stars, 2026-08
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phosphorylated mtor pser2448 antibody  (Assay Biotechnology)
90
Assay Biotechnology phosphorylated mtor pser2448 antibody
Trimethylamine‐ N ‐oxide ( TMAO ) reduced the expression of synaptic plasticity‐related proteins by down‐regulating the activity of the <t>mTOR</t> signalling pathway. (a) Synaptophysin ( SYN ), postsynaptic density 95 ( PSD ‐95) and N ‐methyl‐ d ‐aspartate 1 ( NMDAR 1) were shown by immunohistochemical staining in the hippocampus. The expression levels of SYN , NMDAR 1 and PSD ‐95 were significantly decreased in the P8‐C group compared with the R1‐C group. There was a significant decrease in the expression of these synaptic‐associated proteins in the TMAO groups compared with their control groups (scale bar = 50 μm). (b) The expression levels of SYN , NMDAR 1 and PSD ‐95 were assayed by Western blotting. To examine the possible mechanism involved in the decline of synaptic‐associated proteins, three proteins ( mTOR <t>,</t> <t>p70s6k</t> and 4 EBP 2) of the mTOR signalling pathway were assessed by RT – PCR and Western blotting. (Figure A) The mRNA levels of mTOR , p70s6k and 4 EBP 2 were not significantly different in the groups assessed by RT – PCR . (c) Phosphor‐ mTOR / mTOR , phosphor‐p70s6k/p70s6k and phosphor‐4 EBP 1/4 EBP 2 were monitored by Western blotting. β‐Actin was used as a loading control. The bands in the Western blotting were scanned, and the ratios of optical density of specific bands and β‐actin are illustrated. TMAO inhibited the active form of mTOR , p70s6k and 4 EBP 2 (phosphorylated). Data are shown as the mean ± SEM ( n = 6 each group, two‐way ANOVA , comparisons between two groups were made using Tukey's multiple comparison test. ** p < .01). The samples derived from the same experiment and the blots were processed in parallel
Phosphorylated Mtor Pser2448 Antibody, supplied by Assay Biotechnology, used in various techniques. Bioz Stars score: 90/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
https://www.bioz.com/product/phosphorylated+mtor/pm31722347-68-8-11?v=Assay+Biotechnology
Average 90 stars, based on 1 article reviews
phosphorylated mtor pser2448 antibody - by Bioz Stars, 2026-08
90/100 stars
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Image Search Results


Trimethylamine‐ N ‐oxide ( TMAO ) reduced the expression of synaptic plasticity‐related proteins by down‐regulating the activity of the mTOR signalling pathway. (a) Synaptophysin ( SYN ), postsynaptic density 95 ( PSD ‐95) and N ‐methyl‐ d ‐aspartate 1 ( NMDAR 1) were shown by immunohistochemical staining in the hippocampus. The expression levels of SYN , NMDAR 1 and PSD ‐95 were significantly decreased in the P8‐C group compared with the R1‐C group. There was a significant decrease in the expression of these synaptic‐associated proteins in the TMAO groups compared with their control groups (scale bar = 50 μm). (b) The expression levels of SYN , NMDAR 1 and PSD ‐95 were assayed by Western blotting. To examine the possible mechanism involved in the decline of synaptic‐associated proteins, three proteins ( mTOR , p70s6k and 4 EBP 2) of the mTOR signalling pathway were assessed by RT – PCR and Western blotting. (Figure A) The mRNA levels of mTOR , p70s6k and 4 EBP 2 were not significantly different in the groups assessed by RT – PCR . (c) Phosphor‐ mTOR / mTOR , phosphor‐p70s6k/p70s6k and phosphor‐4 EBP 1/4 EBP 2 were monitored by Western blotting. β‐Actin was used as a loading control. The bands in the Western blotting were scanned, and the ratios of optical density of specific bands and β‐actin are illustrated. TMAO inhibited the active form of mTOR , p70s6k and 4 EBP 2 (phosphorylated). Data are shown as the mean ± SEM ( n = 6 each group, two‐way ANOVA , comparisons between two groups were made using Tukey's multiple comparison test. ** p < .01). The samples derived from the same experiment and the blots were processed in parallel

Journal: Aging Cell

Article Title: Trimethylamine‐ N ‐oxide promotes brain aging and cognitive impairment in mice

doi: 10.1111/acel.12768

Figure Lengend Snippet: Trimethylamine‐ N ‐oxide ( TMAO ) reduced the expression of synaptic plasticity‐related proteins by down‐regulating the activity of the mTOR signalling pathway. (a) Synaptophysin ( SYN ), postsynaptic density 95 ( PSD ‐95) and N ‐methyl‐ d ‐aspartate 1 ( NMDAR 1) were shown by immunohistochemical staining in the hippocampus. The expression levels of SYN , NMDAR 1 and PSD ‐95 were significantly decreased in the P8‐C group compared with the R1‐C group. There was a significant decrease in the expression of these synaptic‐associated proteins in the TMAO groups compared with their control groups (scale bar = 50 μm). (b) The expression levels of SYN , NMDAR 1 and PSD ‐95 were assayed by Western blotting. To examine the possible mechanism involved in the decline of synaptic‐associated proteins, three proteins ( mTOR , p70s6k and 4 EBP 2) of the mTOR signalling pathway were assessed by RT – PCR and Western blotting. (Figure A) The mRNA levels of mTOR , p70s6k and 4 EBP 2 were not significantly different in the groups assessed by RT – PCR . (c) Phosphor‐ mTOR / mTOR , phosphor‐p70s6k/p70s6k and phosphor‐4 EBP 1/4 EBP 2 were monitored by Western blotting. β‐Actin was used as a loading control. The bands in the Western blotting were scanned, and the ratios of optical density of specific bands and β‐actin are illustrated. TMAO inhibited the active form of mTOR , p70s6k and 4 EBP 2 (phosphorylated). Data are shown as the mean ± SEM ( n = 6 each group, two‐way ANOVA , comparisons between two groups were made using Tukey's multiple comparison test. ** p < .01). The samples derived from the same experiment and the blots were processed in parallel

Article Snippet: This process is mediated by phosphorylation of two major downstream targets of mTOR, p70s6 kinase (p70s6k) and eIF4E‐binding protein (4EBP2) (Garelick & Kennedy, ).

Techniques: Expressing, Activity Assay, Immunohistochemical staining, Staining, Control, Western Blot, Reverse Transcription Polymerase Chain Reaction, Comparison, Derivative Assay